<論文紹介:NEJM 2020;383:68-74.他>

NEJMがとても役立ちますよ、ということを以前お話ししましたが、
最新号から論文を紹介します。

CLINICAL PROBLEM-SOLVING: Cryptic Cachexia.(NEJM 2020;383:68-74.)
NEJMでは、よく症例検討として出題される病態です。
相変わらず難しいし、私にはこのCT所見の解釈すら分かりませんでした。

CORRESPONDENCE: Variant Creutzfeldt–Jakob Disease Diagnosed 7.5 Years after Occupational Exposure.(NEJM 2020;383:83-85.)
これで感染して死に至るって、とても怖いのですが、、、。

 

ついでに、最近のNEJM論文も紹介します。

REVIEW ARTICLE: Down Syndrome.(NEJM 2020;382:2344-2352.)
Down Syndromeの総説です。

CLINICAL PROBLEM-SOLVING: The Game Is Afoot.(NEJM 2020;382:2249-2255.)
教育的な典型的症例です。

Case 15-2020: A 79-Year-Old Man with Hyponatremia and Involuntary Movements of the Arm and Face.(NEJM 2020;382:1943-1950.)
症状は典型的ですが、画像掲載はありません。
面白いのは、回答者がPubmedでキーワードを工夫して入力し検索して解答を見つけた、と正直に答えている点です。
たぶん、他のCaseの回答者も同じようにしていると思うのですが、これほどはっきり(繰り返し検索したことを含め)正直に告白した回答者は今まで目にしたことがないような、、、。

 

 

他のNEJM関連は、こちら。
(かなり数がたまったので今後はリンクははりません。ご了承ください。
内容を記載しますので、ご関心があればリンク先アドレスをコピペしてご参照ください。)

(https://ocu-radiology.jp/news/news-2903/)
Fascioliasis (Eosinophilia).
Proteinase 3 antineutrophil cytoplasmic antibody–associated vasculitis consistent with granulomatosis with polyangiitis.
Hantavirus cardiopulmonary syndrome.
PSA Screening.

(https://ocu-radiology.jp/news/news-2788/)
Intraparenchymal and intracranial hemorrhage presumably due to birth trauma.
小児虐待.
Pulmonary tumor thrombotic microangiopathy

(https://ocu-radiology.jp/news/news-2758/)
A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Treatment for Spontaneous Pneumothorax.
Fatal Cytomegalovirus Infection with Inherited NOS2 Deficiency.
Strongyloidiasis with human T-lymphotropic virus type 1 infection.
Disseminated coccidioidomycosis and ANCA-associated glomerulonephritis.
Photopheresis for Colitis Induced by Checkpoint-Inhibitor Therapy.
Machine Learning and the Cancer-Diagnosis Problem.
Diffuse pulmonary alveolar hemorrhage with focal infarction with vaping.

(https://ocu-radiology.jp/news/news-2601/):
Identification of Anonymous MRI Research Participants with Face-Recognition Software.
Cerebellar form of Creutzfeldt–Jakob disease.
Adenovirus meningoencephalitis.
Imaging of Vaping-Associated Lung Disease.

(https://ocu-radiology.jp/news/news-2550/):
Interstitial lung disease associated with FLNA mutation.
Spondyloarthritis in patients with inflammatory bowel disease (Crohn’s disease).
Inhaled GM-CSF for Pulmonary Alveolar Proteinosis.

(https://ocu-radiology.jp/news/news-2464/):
Pregnant woman with Acute suppurative appendicitis and periappendicitis.
Pheochromocytoma and Paraganglioma.
Drug-Induced Liver Injury.
New Guidelines for Statistical Reporting in the Journal.

(https://ocu-radiology.jp/news/news-2436/):
Leber’s hereditary optic neuropathy.
Kelch-like Protein 11 Antibodies in Seminoma-Associated Paraneoplastic Encephalitis.
Intestinal tuberculosis.

(https://ocu-radiology.jp/news/news-2403/):
Anaplastic carcinoma arising in association with intestinal-type mucinous carcinoma of the ovary.
(いわゆる Mucinous cystic tumours with mural nodules)
West Nile virus encephalitis/West Nile virus meningoencephalitis.

(https://ocu-radiology.jp/news/news-2371):
Systemic lupus erythematosus.
Contrast-Associated Acute Kidney Injury.
Mesenchymal Hamartoma of the Liver and DICER1 Syndrome.
Metastatic postpubertal immature teratoma.
Machine Learning in Medicine.

(https://ocu-radiology.jp/news/news-2148/):
Idiopathic pulmonary fibrosis.
Pulmonary alveolar proteinosis.
Mucinous Ovarian Carcinoma.
Ocular syphilis.

(https://ocu-radiology.jp/news/news-2115/):
Herpes simplex virus lymphadenitis, Chronic lymphocytic leukemia.
Perforation of the sigmoid colon by a foreign body (toothpick) that caused a fistula to the right common iliac artery.
Powassan virus encephalitis.

(https://ocu-radiology.jp/news/news-2037/):
Papulonecrotic tuberculid (cutaneous tuberculosis).
Hepatobiliary Tuberculosis.
Sudden death caused by pulmonary fat embolism in a patient with miliary tuberculosis.

(https://ocu-radiology.jp/news/news-1974/):
眼窩領域Granulomatosis with polyangiitis, Susac’s syndrome.
Clostridium perfringens bacteremia with a hepatic abscess.
Osteoblastic and Osteolytic Spine Metastases by Using SWI.

(https://ocu-radiology.jp/news/news-1921/):
The t(6;11) TFEB translocation variant of renal-cell carcinoma.
比較的新しい病理組織概念でUncommonな腎腫瘤の復習.

(https://ocu-radiology.jp/news/news-1901/):
Pulmonary adenocarcinoma, hypercoagulable state with nonbacterial thrombotic endocarditis.
BK Virus–Progressive Multifocal Leukoencephalopathy.

(https://ocu-radiology.jp/news/news-1843/):
Anti–N-methyl-d-aspartate (NMDA) receptor encephalitis.
The drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, associated with human herpesvirus 6.
Acute Viral Encephalitis. 特にarbovirus encephalitisについて.

(https://ocu-radiology.jp/news/news-1793/):
Vitamin C deficiency (scurvy).“bachelor scurvy”
Vitamin B6, folate, zinc, and selenium deficiencies.
Alcohol-use disorder.
Multiple vitamin deficiencies.

(https://ocu-radiology.jp/news/news-1681/):
Polyarteritis nodosa. HBVとの関連.

(https://ocu-radiology.jp/news/news-1605/):
Membranous nephropathy, PLA2R type. IgG4との関連性など.
Idiopathic Pulmonary Fibrosis.

(https://ocu-radiology.jp/news/news-1588/):
Giant-cell myocarditis.
Takotsubo cardiomyopathy and catecholamine-induced crisis due to pheochromocytoma.
Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

(https://ocu-radiology.jp/news/news-1462/):
Homocystinuriaの様々な表現型:Cystathionine β-synthase deficiency, Methylenetetrahydrofolate reductase deficiency.
Primary Sjögren’s Syndrome.
Antibody-Mediated Encephalitis.

(https://ocu-radiology.jp/news/news-1374/):
Immune-Related Adverse Events Associated with Immune Checkpoint Blockade.
Multiple Sclerosis. Neuromyelitis Optica Spectrum Disorders.
Adenovirus infection, disseminated.

(https://ocu-radiology.jp/news/news-1253/):
Biotin–thiamine–responsive basal ganglia disease.

(https://ocu-radiology.jp/news/news-1109/):
好酸球増多症(Eosinophilia)について.

(https://ocu-radiology.jp/news/news-897/):
Copper deficiency. Zincとの関連.

(https://ocu-radiology.jp/news/news-891/):
Takayasu’s arteritis.
Atypical immunoblastic reaction that was consistent with primary Epstein–Barr virus infection.

(https://ocu-radiology.jp/news/news-783/):
NEJMの紹介、Case Recordsの変遷についての私見.