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<論文紹介:NEJM 2020;382:1844-1849.他>

NEJMがとても役立ちますよ、ということを以前お話ししましたが、
最新号から論文を紹介します。

CLINICAL PROBLEM-SOLVING: Hiding in the Water.(NEJM 2020;382:1844-1849.)

日本でも、ときどき出会う症例です。
画像も比較的典型的で教育的です。
今回の症例に関しては、(https://ocu-radiology.jp/news/news-1109/)も復習に役立つと思います。

ついでに、最近のNEJM論文も紹介します。

Case 14-2020: A 37-Year-Old Man with Joint Pain and Eye Redness.(NEJM 2020;382:1750-1758.)

有名な病態も、こういった表現型をとるんですね。

Case 12-2020: A 24-Year-Old Man with Fever, Cough, and Dyspnea.(NEJM 2020;382:1544-1553.)

出会うことはとてもまれだと思いますが、
それにしてもややこしいHistoryです。

MEDICINE AND SOCIETY: Reconsidering Prostate Cancer Mortality — The Future of PSA Screening.(NEJM 2020;382:1557-1563.)

PSAスクリーニングの問題点が大変よくわかります。
これに対応するMRI検査に関してもきっちり考えた方がよいのではと感じます。

最近の3-4月のCase Recordsは、感染症関連ばかりでした。
疫学や背景と合わせて考えていかねば、と思います。

 

 

他のNEJM関連は、こちら。
(かなり数がたまったので今後はリンクははりません。ご了承ください。
内容を記載しますので、ご関心があればリンク先アドレスをコピペしてご参照ください。)

(https://ocu-radiology.jp/news/news-2788/)
Intraparenchymal and intracranial hemorrhage presumably due to birth trauma.
小児虐待.
Pulmonary tumor thrombotic microangiopathy

(https://ocu-radiology.jp/news/news-2758/)
A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Treatment for Spontaneous Pneumothorax.
Fatal Cytomegalovirus Infection with Inherited NOS2 Deficiency.
Strongyloidiasis with human T-lymphotropic virus type 1 infection.
Disseminated coccidioidomycosis and ANCA-associated glomerulonephritis.
Photopheresis for Colitis Induced by Checkpoint-Inhibitor Therapy.
Machine Learning and the Cancer-Diagnosis Problem.
Diffuse pulmonary alveolar hemorrhage with focal infarction with vaping.

(https://ocu-radiology.jp/news/news-2601/):
Identification of Anonymous MRI Research Participants with Face-Recognition Software.
Cerebellar form of Creutzfeldt–Jakob disease.
Adenovirus meningoencephalitis.
Imaging of Vaping-Associated Lung Disease.

(https://ocu-radiology.jp/news/news-2550/):
Interstitial lung disease associated with FLNA mutation.
Spondyloarthritis in patients with inflammatory bowel disease (Crohn’s disease).
Inhaled GM-CSF for Pulmonary Alveolar Proteinosis.

(https://ocu-radiology.jp/news/news-2464/):
Pregnant woman with Acute suppurative appendicitis and periappendicitis.
Pheochromocytoma and Paraganglioma.
Drug-Induced Liver Injury.
New Guidelines for Statistical Reporting in the Journal.

(https://ocu-radiology.jp/news/news-2436/):
Leber’s hereditary optic neuropathy.
Kelch-like Protein 11 Antibodies in Seminoma-Associated Paraneoplastic Encephalitis.
Intestinal tuberculosis.

(https://ocu-radiology.jp/news/news-2403/):
Anaplastic carcinoma arising in association with intestinal-type mucinous carcinoma of the ovary.
(いわゆる Mucinous cystic tumours with mural nodules)
West Nile virus encephalitis/West Nile virus meningoencephalitis.

(https://ocu-radiology.jp/news/news-2371):
Systemic lupus erythematosus.
Contrast-Associated Acute Kidney Injury.
Mesenchymal Hamartoma of the Liver and DICER1 Syndrome.
Metastatic postpubertal immature teratoma.
Machine Learning in Medicine.

(https://ocu-radiology.jp/news/news-2148/):
Idiopathic pulmonary fibrosis.
Pulmonary alveolar proteinosis.
Mucinous Ovarian Carcinoma.
Ocular syphilis.

(https://ocu-radiology.jp/news/news-2115/):
Herpes simplex virus lymphadenitis, Chronic lymphocytic leukemia.
Perforation of the sigmoid colon by a foreign body (toothpick) that caused a fistula to the right common iliac artery.
Powassan virus encephalitis.

(https://ocu-radiology.jp/news/news-2037/):
Papulonecrotic tuberculid (cutaneous tuberculosis).
Hepatobiliary Tuberculosis.
Sudden death caused by pulmonary fat embolism in a patient with miliary tuberculosis.

(https://ocu-radiology.jp/news/news-1974/):
眼窩領域Granulomatosis with polyangiitis, Susac’s syndrome.
Clostridium perfringens bacteremia with a hepatic abscess.
Osteoblastic and Osteolytic Spine Metastases by Using SWI.

(https://ocu-radiology.jp/news/news-1921/):
The t(6;11) TFEB translocation variant of renal-cell carcinoma.
比較的新しい病理組織概念でUncommonな腎腫瘤の復習.

(https://ocu-radiology.jp/news/news-1901/):
Pulmonary adenocarcinoma, hypercoagulable state with nonbacterial thrombotic endocarditis.
BK Virus–Progressive Multifocal Leukoencephalopathy.

(https://ocu-radiology.jp/news/news-1843/):
Anti–N-methyl-d-aspartate (NMDA) receptor encephalitis.
The drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, associated with human herpesvirus 6.
Acute Viral Encephalitis. 特にarbovirus encephalitisについて.

(https://ocu-radiology.jp/news/news-1793/):
Vitamin C deficiency (scurvy).“bachelor scurvy”
Vitamin B6, folate, zinc, and selenium deficiencies.
Alcohol-use disorder.
Multiple vitamin deficiencies.

(https://ocu-radiology.jp/news/news-1681/):
Polyarteritis nodosa. HBVとの関連.

(https://ocu-radiology.jp/news/news-1605/):
Membranous nephropathy, PLA2R type. IgG4との関連性など.
Idiopathic Pulmonary Fibrosis.

(https://ocu-radiology.jp/news/news-1588/):
Giant-cell myocarditis.
Takotsubo cardiomyopathy and catecholamine-induced crisis due to pheochromocytoma.
Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

(https://ocu-radiology.jp/news/news-1462/):
Homocystinuriaの様々な表現型:Cystathionine β-synthase deficiency, Methylenetetrahydrofolate reductase deficiency.
Primary Sjögren’s Syndrome.
Antibody-Mediated Encephalitis.

(https://ocu-radiology.jp/news/news-1374/):
Immune-Related Adverse Events Associated with Immune Checkpoint Blockade.
Multiple Sclerosis. Neuromyelitis Optica Spectrum Disorders.
Adenovirus infection, disseminated.

(https://ocu-radiology.jp/news/news-1253/):
Biotin–thiamine–responsive basal ganglia disease.

(https://ocu-radiology.jp/news/news-1109/):
好酸球増多症(Eosinophilia)について.

(https://ocu-radiology.jp/news/news-897/):
Copper deficiency. Zincとの関連.

(https://ocu-radiology.jp/news/news-891/):
Takayasu’s arteritis.
Atypical immunoblastic reaction that was consistent with primary Epstein–Barr virus infection.

(https://ocu-radiology.jp/news/news-783/):
NEJMの紹介、Case Recordsの変遷についての私見.