NEJMがとても役立ちますよ、ということを以前お話ししましたが、
最近のNEJM論文を紹介します。

「CLINICAL PRACTICE: Adrenal Incidentaloma.（NEJM 2021;384:1542-1551.）」

副腎偶発腫瘍の対応方法の解説です。
Nonfunctioning adrenal tumors that have an attenuation of 10 Hounsfield units or less on computed tomographic (CT) evaluation and that are smaller than 4 cm in greatest diameter generally do not warrant intervention or long-term follow-up.

「Case 11-2021: A 39-Year-Old Woman with Fever, Flank Pain, and Inguinal Lymphadenopathy.（NEJM 2021;384:1448-1456.）」
画像から討論までとても勉強になり、必読です。

「CLINICAL PROBLEM-SOLVING: Stalking the Diagnosis.（NEJM 2021;384:1262-1267.）」
最初に画像を隅から隅まで丁寧に読影していたら診断は遅れなかったと思います。

「REVIEW ARTICLE: Extrahepatic Manifestations of Chronic HCV Infection. （NEJM 2021;384:1038-1052.）」
Fig 1が役立ちます。Sicca syndromeが生じることは知りませんでした。

「CLINICAL PROBLEM-SOLVING: A Treacherous Course.（NEJM 2021;384:860-865.）」
この気管支血管束に沿うようなスリガラス影のCT所見は、比較的特徴的な印象が あります。

 

他のNEJM関連は、こちら。
（かなり数がたまったので今後はリンクははりません。ご了承ください。
内容を記載しますので、ご関心があればリンク先アドレスをコピペしてご参照く ださい。）

（https://ocu-radiology.jp/news/news-3212/）
Lymphoplasmacytic lymphoma of the central nervous system (Bing–Neel syndrome).
Disseminated Mycobacterium bovis infection.
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia.
Systemic primary amyloidosis.

（https://ocu-radiology.jp/news/news-3133/）
Mycobacterium tuberculosis meningitis.
Vaginal Transmission of Cancer from Mothers with Cervical Cancer to Infants.
Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease.
Cryptococcal meningoencephalitis and advanced human immunodeficiency virus infection.

（https://ocu-radiology.jp/news/news-3082/）
Primary hyperparathyroidism due to an ectopic parathyroid carcinoma.
Necrotizing granulomatous lymphadenitis due to Mycobacterium tuberculosis complex.
Tuberculous pericarditis.
Aceruloplasminemia, hereditary.
Sensory Ganglionopathy.
Borrelia miyamotoi infection.
Autophagy in Human Diseas

（https://ocu-radiology.jp/news/news-3050/）
Disseminated cryptococcosis.
Cryptococcus neoformans.
Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency.
boric acid toxicity.
Human immunodeficiency virus type 2 infection and cerebral toxoplasmosis.
New-Onset Diabetes in Covid-19.

（https://ocu-radiology.jp/news/news-3023/）
Pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Lead poisoning.
Acute Ischemic Stroke.
Degenerative Cervical Spondylosis.

（https://ocu-radiology.jp/news/news-2980/）
Whipple’s disease.
Variant Creutzfeldt–Jakob Disease.
Down Syndrome.
Phosphaturic mesenchymal tumor.
LGI1 autoimmune encephalitis.

（https://ocu-radiology.jp/news/news-2903/）
Fascioliasis (Eosinophilia).
Proteinase 3 antineutrophil cytoplasmic antibody–associated vasculitis consistent with granulomatosis with polyangiitis.
Hantavirus cardiopulmonary syndrome.
PSA Screening.

（https://ocu-radiology.jp/news/news-2788/）
Intraparenchymal and intracranial hemorrhage presumably due to birth trauma.
小児虐待.
Pulmonary tumor thrombotic microangiopathy

（https://ocu-radiology.jp/news/news-2758/）
A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Treatment for Spontaneous Pneumothorax.
Fatal Cytomegalovirus Infection with Inherited NOS2 Deficiency.
Strongyloidiasis with human T-lymphotropic virus type 1 infection.
Disseminated coccidioidomycosis and ANCA-associated glomerulonephritis.
Photopheresis for Colitis Induced by Checkpoint-Inhibitor Therapy.
Machine Learning and the Cancer-Diagnosis Problem.
Diffuse pulmonary alveolar hemorrhage with focal infarction with vaping.

（https://ocu-radiology.jp/news/news-2601/）：
Identification of Anonymous MRI Research Participants with Face-Recognition Software.
Cerebellar form of Creutzfeldt–Jakob disease.
Adenovirus meningoencephalitis.
Imaging of Vaping-Associated Lung Disease.

（https://ocu-radiology.jp/news/news-2550/）：
Interstitial lung disease associated with FLNA mutation.
Spondyloarthritis in patients with inflammatory bowel disease (Crohn’s disease).
Inhaled GM-CSF for Pulmonary Alveolar Proteinosis.

（https://ocu-radiology.jp/news/news-2464/）：
Pregnant woman with Acute suppurative appendicitis and periappendicitis.
Pheochromocytoma and Paraganglioma.
Drug-Induced Liver Injury.
New Guidelines for Statistical Reporting in the Journal.

（https://ocu-radiology.jp/news/news-2436/）：
Leber’s hereditary optic neuropathy.
Kelch-like Protein 11 Antibodies in Seminoma-Associated Paraneoplastic Encephalitis.
Intestinal tuberculosis.

（https://ocu-radiology.jp/news/news-2403/）：
Anaplastic carcinoma arising in association with intestinal-type mucinous carcinoma of the ovary.
（いわゆる　Mucinous cystic tumours with mural nodules）
West Nile virus encephalitis/West Nile virus meningoencephalitis.

（https://ocu-radiology.jp/news/news-2371）：
Systemic lupus erythematosus.
Contrast-Associated Acute Kidney Injury.
Mesenchymal Hamartoma of the Liver and DICER1 Syndrome.
Metastatic postpubertal immature teratoma.
Machine Learning in Medicine.

（https://ocu-radiology.jp/news/news-2148/）：
Idiopathic pulmonary fibrosis.
Pulmonary alveolar proteinosis.
Mucinous Ovarian Carcinoma.
Ocular syphilis.

（https://ocu-radiology.jp/news/news-2115/）：
Herpes simplex virus lymphadenitis, Chronic lymphocytic leukemia.
Perforation of the sigmoid colon by a foreign body (toothpick) that caused a fistula to the right common iliac artery.
Powassan virus encephalitis.

（https://ocu-radiology.jp/news/news-2037/）：
Papulonecrotic tuberculid (cutaneous tuberculosis).
Hepatobiliary Tuberculosis.
Sudden death caused by pulmonary fat embolism in a patient with miliary tuberculosis.

（https://ocu-radiology.jp/news/news-1974/）：
眼窩領域Granulomatosis with polyangiitis, Susac’s syndrome.
Clostridium perfringens bacteremia with a hepatic abscess.
Osteoblastic and Osteolytic Spine Metastases by Using SWI.

（https://ocu-radiology.jp/news/news-1921/）：
The t(6;11) TFEB translocation variant of renal-cell carcinoma.
比較的新しい病理組織概念でUncommonな腎腫瘤の復習.

（https://ocu-radiology.jp/news/news-1901/）：
Pulmonary adenocarcinoma, hypercoagulable state with nonbacterial thrombotic endocarditis.
BK Virus–Progressive Multifocal Leukoencephalopathy.

（https://ocu-radiology.jp/news/news-1843/）：
Anti–N-methyl-d-aspartate (NMDA) receptor encephalitis.
The drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, associated with human herpesvirus 6.
Acute Viral Encephalitis. 特にarbovirus encephalitisについて.

（https://ocu-radiology.jp/news/news-1793/）：
Vitamin C deficiency (scurvy).“bachelor scurvy”
Vitamin B6, folate, zinc, and selenium deficiencies.
Alcohol-use disorder.
Multiple vitamin deficiencies.

（https://ocu-radiology.jp/news/news-1681/）：
Polyarteritis nodosa. HBVとの関連.

（https://ocu-radiology.jp/news/news-1605/）：
Membranous nephropathy, PLA2R type. IgG4との関連性など.
Idiopathic Pulmonary Fibrosis.

（https://ocu-radiology.jp/news/news-1588/）：
Giant-cell myocarditis.
Takotsubo cardiomyopathy and catecholamine-induced crisis due to pheochromocytoma.
Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

（https://ocu-radiology.jp/news/news-1462/）：
Homocystinuriaの様々な表現型：Cystathionine β-synthase deficiency, Methylenetetrahydrofolate reductase deficiency.
Primary Sjögren’s Syndrome.
Antibody-Mediated Encephalitis.

（https://ocu-radiology.jp/news/news-1374/）：
Immune-Related Adverse Events Associated with Immune Checkpoint Blockade.
Multiple Sclerosis. Neuromyelitis Optica Spectrum Disorders.
Adenovirus infection, disseminated.

（https://ocu-radiology.jp/news/news-1253/）：
Biotin–thiamine–responsive basal ganglia disease.

（https://ocu-radiology.jp/news/news-1109/）：
好酸球増多症（Eosinophilia）について.

（https://ocu-radiology.jp/news/news-897/）：
Copper deficiency. Zincとの関連.

（https://ocu-radiology.jp/news/news-891/）：
Takayasu’s arteritis.
Atypical immunoblastic reaction that was consistent with primary Epstein–Barr virus infection.

（https://ocu-radiology.jp/news/news-783/）：
NEJMの紹介、Case Recordsの変遷についての私見.